CHRONIC DERMATOSES OF THE EXTERNAL AUDITORY CANAL: HOW TO ACHIEVE RECOVERY OR LONG-TERM REMISSION

Pukhlik SM, Tagunova IK, Andreev OV

Odessa National Medical University

Email: lor@te.net.ua

Abstract

Topicality: Ear dermatitis is a common skin condition that can affect the entire ear, including the lobe, pinna, external auditory canal, and eardrum. Occurs in people with a genetic predisposition, disorders in the work of the immune system, peculiarities of the body’s response at the level of various organs and systems, presence of yeast fungus on the skin, more often affects the elderly. The therapeutic approach depends on the type and area of ​​localization of skin lesions, the reason that caused them. Local preparations containing a combination of corticosteroids, antibiotics and antimycotics are used, which are used in acute pathology. With chronic, non-manifest processes, these drugs are not always acceptable, therefore, the search for new and effective drugs that have anti-inflammatory activity without the use of antibiotics and hormones, can be used for complex therapy of ear dermatitis is an urgent task.

The purpose of the study is to improve the quality of treatment of patients with chronic ear dermatitis by using natural drugs that have anti-inflammatory, stimulating and regenerative properties.

Concept of work: data collected as a result of fastening, treatment and care of 45 patients with chronic ear dermatitis, who were divided into 2 groups: main – 30 persons (20 male patients, 10 – female, the middle age became 58); and control – 15 persons (10 male patients, 5 female patients, the middle age – 57 years old). Diagnosis was based on the data of otoscopy, dermatoscopy, bacteriological investigation, clinical testing (to identify concomitant illnesses), the level of IgE in the blood and specific IgE in blood serum. The therapy was aimed at reducing the sign of illness, aggravation of accompanying symptoms, especially soreness, and maintaining remission with treatment. Most often, illness occurred in elderly patients with a high susceptibility to infectious skin lesions. Based on the data of bacteriological investigation of water-reinforced ear, it was most often revealed Staphylococcus aureus, proliferation of yeast-like fungi (such as Malassezia spp., Candida albicans, Rhodotorula rubra). Immunological research data: shift in the level of IgE from gas and specific to yeast-like fungi in blood serum. Typically, if we suffer from fungal infections of the skin with allergic manifestations, we are prescribed medications with corticosteroids. However, contraindications before the recognition of topical CS are associated with the risk of developing secondary infections due to decreased local resistance and atrophic changes in the skin, fungal infections: bacterial and viral. To reduce the need for medication during the period of prolonged treatment and support of remission, used ear drops “Otogut squalene” which have an acidic content, pH is more than 5-6, which is very important for antibacterial and dry action. In the main group (30 patients), after a course of standard treatment, as a supportive therapy, 2 times a day, after sanitation of the auditory canal, ear drops “Otogut squalene” were applied, 4 drops endoaurally, monitored the condition of the patients. Study of long-term results of treatment The study of the long-term results of treatment in the main group and in the control group over the course of one day, allowed us to confirm that supportive therapy with ear drops “Otogut squalene”, reduces the severity of the inflammation, prevents the manifestation of illness, reduces the elasticity of the skin of the ear canal. It reduces the severity of the disease in patients with epidermal plugs, which significantly improves the quality of life of patients and allows for a complete remission.

Conclusions:

1. Insufficient attention to the etiopathogenesis of ear dermatitis, which means difficult treatment of this pathology, will require a significant arsenal of topical methods.
2. Therapy for dermatitis may be complex and include: elimination approaches, diet, hypoallergenic regimen, local and systemic pharmacotherapy, correction of associated pathology.
3. The work carried out on observation and comparison of the results of treatment with the use of the drug “Otogut squalene” allows it to be included in the arsenal of means used for the treatment of ear dermatitis and allows to achieve long-term remission, to make the rehabilitation of the skin of the auditory canal as effective and high-quality as possible.

Keywords: otitis externa, dermatosis of the auditory canal, topical treatment, squalene.