№4(6) 2023

DOI 10.37219/2528-8253-2023-4-91

Yevcheva AF, Pukhlik SM

CLINICAL MISTAKES IN THE DIAGNOSTICS OF MALIGNANT NEOPLASMS OF THE HUMAN SKIN

Yevcheva Anhelina F.
Odesa National Medical University
e-mail: dr.yevchev@ukr.netPukhlik

Sergey M
Odessa National Medical University
Head of the Department of Otorhinolaryngology
Doctor of Medical Sciences, Professor
E-mail: lor@te.net.ua
Orchid ID: http://orcid.org/0000-0001-7196-9642
Scopus Author ID: 6506298353

Abstract

Purpose: practical comparison of the complex of diagnostic elements of a malignant human skin disease with the final morphological study to determine errors in their diagnosis.

Materials and methods: 85 patients with skin disease were observed, who had clinical examination and morphological examination after surgical removal of a skin tumor from 2018 to 2022. 85 patients were involved in the study. Clinical research included 25 women and 60 men, aged from 56 to 80 years. From the anamnesis, all formations were subjected to physical irritation of varying degrees, which may have prompted the aggressive development of the malignant process.

Results and discussion: Out of 85 patients, 43 patients were morphologically diagnosed with skin cancer, which accounted for (50.6%). Of these, 21 (48.8%) patients had basal cell carcinoma (BCC) and 22 (51.2%) had squamous cell carcinoma of the skin (SCC). The second group of patients – 39 (45.9%) had pigmented keratosis of the skin and only 3 patients had skin cancer of the abdominal wall, which was 3.5%.

The final results showed that the clinical semiotics did not always coincide with the morphological examination. It was in 39 patients, which amounted to 45.9% of the error.

Observation of patients with skin cancer of the face and abdominal wall for 3-5 years showed a satisfactory quality of life in all patients with malignant skin tumors, without signs of recurrence. And because no signs of relapse were observed, which confirmed that the patients were cured and it was recommended to exclude harmful actions – industrial and solar actions. But the unconfirmed malignant process of the skin testifies to the increased oncological vigilance of oncologists, and this is gratifying.

Keywords: malignant skin tumors, diagnosis, clinical errors.

References

    1. Yevcheva AF. [Modern diagnostics of face and neck skin neoplasma]. Otorhinolaryngology. 2019;2(2-3):47-52. doi 10.37219/2528-8253-2019-2-47. [Article in Ukrainian].
    2. Cancer in Ukraine, 2018-2019. Incidence, mortality, activities of oncological service. http://www.ncru.inf.ua/publications/BULL_21/index_e.htm.
    3. [Unified clinical protocol for primary, secondary (specialised), tertiary (highly specialised) medical care basal cell skin cancer]. Order of the Ministry of Health of Ukraine dated 28.03.2016 No. 246. https://ips.ligazakon.net/document/view/MOZ25865?an=1&ed=2016_03_28. [In Ukrainian].
    4. Gross K, Steinman HK, editors. Mohs Surgery and Histopathology: Beyond the Fundamentals. Cambridge University Press; 2009. 198 p.
    5. Yevchev FD, Yevcheva AF. [Etiology, pathogenesis, clinical semiotics and diagnostics of skin neoplasms of the head, neck and body. Part 1]. Zhurnal ushnyh, nosovyh i gorlovyh boleznej. 2018;(1):76-82. [Article in Ukrainian].
    6. Yevchev FD, Zabolotniy DI, Yevcheva AF. [Diagnosis and treatment of patients with malignant neoplasms of the external nose and ear and body. Educational and methodological manual]. Odesa: Astroprint; 2021. 184 p. [In Ukrainian].
    7. Yevcheva AF, Pukhlik SM. [Clinical signs and treatment management in malignant processes of the skin of the external nose]. Odes’kij medičnij žurnal. 2021;(6):43-8. doi: 10.54229/2226-2008-2021-6-8. [Article in Ukrainian].